References
[1] Jager T, Albert C, Preuss T, Ashauer R. 2011. General Unified Threshold Model of Survival-a Toxicokinetic-Toxicodynamic Framework for Ecotoxicology. Environ. Sci. Technol. 45:2529–2540.
[2] Ashauer R, Albert C, Augustine S, Cedergreen N, Charles S, Ducrot V, Focks A, Gabsi F, Gergs A, Goussen B, Jager T, Kramer NI, Nyman A-M, Poulsen V, Reichenberger S, Schäfer RB, Van den Brink PJ, Veltman K, Vogel S, Zimmer EI, Preuss TG. 2016. Modelling survival: exposure pattern, species sensitivity and uncertainty. Nat. Sci. Rep. 6:29178.
[3] EFSA PPR Panel. 2018. Scientific Opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) effect models for regulatory
risk assessment of pesticides for aquatic organisms. EFSA Journal. 16: 5377. Available at
https://www.efsa.europa.eu/en/efsajournal/pub/5377
[4] Nyman A-M, Schirmer K, Ashauer R. 2012. Toxicokinetic-toxicodynamic modelling of survival of Gammarus pulex in multiple pulse exposures to propiconazole:
model assumptions, calibration data requirements and predictive power. Ecotoxicology. 21:1828–1840.
[5] Baudrot V, Veber P, Gence G, Charles S. 2018. Fit GUTS reduced models online: from theory to practice. Integrated Environmental Assessment and Management. 14:625–630.
Staff and Contributors
Sandrine Charles, Professor at University Lyon 1
Virgile Baudrot, Scientific Researcher
Aurélie Siberchicot, Engineer at University Lyon 1
Maud Repellin, bachelor student at University Lyon 1